Nanofiber as a novel vehicle for transdermal delivery of therapeutic agents: challenges and opportunities

Abstract Background Transdermal delivery of drugs is a quite challenging task for pharmaceutical scientists. The transdermal route preferred over the oral due to various advantages like avoidance first-pass effect, non-invasiveness, and high patient compliance. Therefore, it necessary develop an effective carrier system that enables passage drug through dermal barrier. Main body abstract Various novel systems are used enhance permeation variety skin Researchers around globe have explored nanofibers therapeutic agents. Nanofibers designed concentration agents in them promoting their flux layers. Polymeric can be loading both hydrophilic lipophilic drugs. Biopolymer-based been also delivery. They capable controlling release prolonged time. Short conclusion literature presented this review paper provides significant proof will intense impact on different bioactive molecules future. Graphic